Petiveria alliaceae, also spelled as Petiveria alliacea, is known as Anamu herb

Petiveria alliaceae is a perennial herb native to the Amazonian region and used in traditional medicine for different purposes, such as diuretic, antispasmodic and anti-inflammatory.

Crude extracts from a plant known as Petiveria alliacea ( Anamu ) are used extensively as folk medicine in developing countries like Colombia, South America. Petiveria alliaceae herb is used in folk medicine in South America. In the Dominican Republic, it is added to a natural aphrodisiac drink called Mama Juana. As of 2009, we could not find any studies regarding the aphrodisiac properties of Petiveria alliaceae herb. There are several potent aphrodisiac herbs such as eurycoma longifolia, tongkat ali, and mucuna pruriens.

Brazil
Petiveria alliacea is a perennial bush plant that grows widely in Brazil. The roots and leaves of Petiveria alliacea have been used in folk medicine for their antispasmodic, sedative, diuretic and antihelminthic actions.

Role as anxiety treatment
Dual effects of crude extracts obtained from Petiveria alliacea on experimental anxiety in mice.
J Ethnopharmacol. 2010; Blainski A, Piccolo VK, Mello JC, de Oliveira RM. Department of Pharmacy and Pharmacology, State University of Maringá, Maringá, Paraná, Brazil.
Different preparations obtained from P. alliacea have been traditionally used in South America and Brazil for many medical conditions. To investigate the effects of fresh whole plant (WP) extract, aerial part (AP) extract, and root (R) extract obtained from Petiveria alliacea using the elevated plus maze (EPM) model of anxiety in mice. Total flavonoid content present in Petiveria alliacea extracts was also determined. WP, AP, or R (300-900mg/kg) extracts were orally administered to mice 30min before they were subjected to the EPM and open field test. Total flavonoid content present in the extracts was determined by spectrophotometry. The WP extract (300 and 900mg/kg) caused anxiolytic-like effects, and the AP extract (300mg/kg) induced anxiogenic-like effects in mice subjected to the EPM. No effect on anxiety-like behavior was observed with acute administration of the R extract. The content of flavonoids present in the AP extract (1.34%) was almost threefold higher than the flavonoid content present in the WP extract (0.52%). Preparations using different fresh parts of Petiveria alliacea caused opposite effects on experimental anxiety in mice. However, predicting the extent to which flavonoid content present in Petiveria alliacea extracts differentially induces anxiolysis or anxiogenesis in mice was not possible. Further studies will be necessary to elucidate the effects of flavonoids or other substances present in Petiveria alliacea extracts on experimental anxiety.

Petiveria alliaceae research studies
Evaluation of the genotoxic effects of a folk medicine, Petiveria alliacea (Anamu).
Mutat Res. 1992. Hoyos LS, Au WW, Heo MY, Morris DL, Legator MS. University of Cauca, Department of Biology, Papayan, Colombia.
Although Petiveria alliaceae plant is known to contain toxic ingredients potential adverse health effects from its use have not been adequately evaluated. We investigated its genotoxic activities by conducting a sister chromatid exchange (SCE) assay using cells in vitro and in vivo. Our data suggest, therefore, that Petiveria alliaceae contains mutagenic and potentially carcinogenic agents although the medicine is not a potent mutagen. Individuals who consume large amounts of this drug may be at risk for development of health problems. Further studies with cells from exposed individuals and from experimental animals should be conducted to provide a better evaluation of health risk from the use of Petiveria alliaceae herb.

Petiveria alleaceae ( anamú ). Study of the hypoglycemic effect.
Ciencias Medicas,1990. Lores RI. Postgraduate Department, Instituto Superior de Med Interne.  La Habana, Cuba.
The combined phytochemical and pharmaceutical study of Petiveria alleaceae L. has shown the existence in the leaves and stems of the plant of a possible hypoglycemic active principle. Extracts from leaves and stem powder were found to produce a decrease of blood sugar concentration of more than 60% one hour after oral administration in male Balb/C mice weighing 20 g fasted for 48 hours.

Antiviral activity of Petiveria alliacea against the bovine viral diarrhea virus.
Chemotherapy. 2002. Ruffa MJ, Wagner ML, Suriano M, Vicente C, Campos R, Cavallaro L. Cátedra de Virología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Five medicinal plants used in Argentina have been assayed to detect inhibition of viral growth. Antiviral activity of the infusions and methanolic extracts of Aristolochia macroura, Celtis spinosa, Plantago major, Schinus areira, Petiveria alliacea and four extracts obtained from the leaves and stems of the last plant were evaluated by the plaque assay. Bovine viral diarrhea virus is highly prevalent in the cattle population, there are no antiviral compounds available; additionally, it is a viral model of the hepatitis C virus. For these reasons and in view of the results obtained, the isolation and characterization of the antiviral components present in the Petiveria alliacea extracts is worth carrying out in the future.

Petiveria alliaceae composition
Petiveria alliaceae has a number of compounds including gamma-glutamyl dipeptides, dibenzyl trisulphide, S-benzyl phenylmethanethiosulfinate. Thiosulfinates, trisulfides and benzylsulfinic acid in anamu have antimicrobial activity.

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