Petiveria alliaceae, also spelled as Petiveria alliacea, is known as Anamu herb
Petiveria alliaceae is a perennial herb native to the Amazonian region and used in traditional medicine for different purposes, such as diuretic, antispasmodic and anti-inflammatory.
Crude extracts from a plant known as Petiveria alliacea ( Anamu ) are used extensively as folk medicine in developing countries like Colombia, South America. Petiveria alliaceae herb is used in folk medicine in South America. In the Dominican Republic, Petiveria alliaceae is added to a natural aphrodisiac drink called Mama Juana. As of 2009, we could not find any studies regarding the aphrodisiac properties of Petiveria alliaceae herb. There are several potent aphrodisiac herbs such as eurycoma longifolia, tongkat ali, and mucuna pruriens.
Brazil
Petiveria alliacea L (Phytolaccaceae), is a perennial bush plant that grows
widely in Brazil. The roots and leaves of Petiveria
alliacea have been used in folk medicine for
their antispasmodic, sedative, diuretic and antihelminthic actions.
Role as anxiety treatment
Dual effects of crude extracts obtained from Petiveria alliacea L. (Phytolaccaceae)
on experimental anxiety in mice.
J Ethnopharmacol. 2010 Mar 24; Blainski A, Piccolo VK, Mello JC, de Oliveira
RM. Department of Pharmacy and Pharmacology, State University of Maringá, Av.
Colombo no. 5790, 87020-900 Maringá, Paraná, Brazil.
Different preparations obtained from P. alliacea have been traditionally used in
South America and Brazil for many medical conditions. To investigate the effects
of fresh whole plant (WP) extract, aerial part (AP) extract, and root (R)
extract obtained from Petiveria alliacea using the elevated plus maze (EPM)
model of anxiety in mice. Total flavonoid content present in Petiveria alliacea
extracts was also determined. WP, AP, or R (300-900mg/kg) extracts were orally
administered to mice 30min before they were subjected to the EPM and open field
test. Total flavonoid content present in the extracts was determined by
spectrophotometry. The WP extract (300 and 900mg/kg) caused anxiolytic-like
effects, and the AP extract (300mg/kg) induced anxiogenic-like effects in mice
subjected to the EPM. No effect on anxiety-like behavior was observed with acute
administration of the R extract. The content of flavonoids present in the AP
extract (1.34%) was almost threefold higher than the flavonoid content present
in the WP extract (0.52%). Preparations using different fresh parts of Petiveria
alliacea caused opposite effects on experimental anxiety in mice. However,
predicting the extent to which flavonoid content present in Petiveria alliacea
extracts differentially induces anxiolysis or anxiogenesis in mice was not
possible. Further studies will be necessary to elucidate the effects of
flavonoids or other substances present in Petiveria alliacea extracts on
experimental anxiety.
Petiveria alliaceae research studies
Evaluation of the genotoxic effects of a folk medicine,
Petiveria alliacea (Anamu).
Mutat Res. 1992 July. Hoyos LS, Au WW, Heo MY, Morris DL, Legator MS.
University of Cauca, Department of Biology, Papayan, Colombia.
Although Petiveria alliaceae plant is known to contain toxic ingredients
potential adverse health effects from its use have not been adequately
evaluated. We investigated its genotoxic activities by conducting a sister
chromatid exchange (SCE) assay using cells in vitro and in vivo. Our data
suggest, therefore, that Petiveria alliaceae contains mutagenic and potentially
carcinogenic agents although the medicine is not a potent mutagen. Individuals
who consume large amounts of this drug may be at risk for development of health
problems. Further studies with cells from exposed individuals and from
experimental animals should be conducted to provide a better evaluation of
health risk from the use of Petiveria alliaceae herb.
Petiveria alleaceae L. ( anamú ). Study of the hypoglycemic effect.
Ciencias Medicas,1990 Oct-December. Lores RI,
Cires Pujol M. Postgraduate Department, Instituto Superior de Med Interne. La Habana, Cuba.
The combined phytochemical and pharmaceutical study of Petiveria alleaceae L. has shown the existence in the leaves and stems of the plant of a
possible hypoglycemic active principle. Extracts from leaves and stem powder
were found to produce a decrease of blood sugar concentration of more than 60%
one hour after oral administration in male Balb/C mice weighing 20 g fasted for
48 hours.
Antiviral activity of Petiveria alliacea against the
bovine viral diarrhea virus.
Chemotherapy. 2002 July. Ruffa MJ, Perusina M, Alfonso V, Wagner ML, Suriano
M, Vicente C, Campos R, Cavallaro L. Cátedra de Virología, Facultad de Farmacia
y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Five medicinal plants used in Argentina have been assayed to detect inhibition
of viral growth. Antiviral activity of the infusions and methanolic extracts of
Aristolochia macroura, Celtis spinosa, Plantago major, Schinus areira, Petiveria
alliacea and four extracts obtained from the leaves and stems of the last plant
were evaluated by the plaque assay. Bovine
viral diarrhea virus is highly prevalent in the
cattle population, there are no antiviral compounds available; additionally, it
is a viral model of the hepatitis C virus. For these reasons and in view of the
results obtained, the isolation and characterization of the antiviral components
present in the Petiveria alliacea extracts is worth carrying out in the future.
Petiveria alliaceae
composition
Petiveria alliaceae
has a number of compounds including gamma-glutamyl dipeptides,
dibenzyl trisulphide, S-benzyl phenylmethanethiosulfinate. Thiosulfinates,
trisulfides and benzylsulfinic acid in anamu have antimicrobial activity.
Pill web site