Piper Longum spice and herb, Pippali, Indian long pepper

Piper Longum has been used traditionally as a digestive aid, sexual stimulant, general tonic, and mucolytic. Piper longum may also play a role in lowering cholesterol levels. As to sexual enhancement, there are more potent herbs such as maca, eurycoma and muira puama.

Piper longum and cholesterol
Antihyperlipidemic Compounds from the Fruit of Piper longum L.
Phytother Res. 2009 January. Jin Z, Borjihan G, Zhao R, Sun Z, Hammond GB, Uryu T. Institute of Macromolecular Chemistry and Mongolian Medicine, Inner Mongolia University, Huhhot 010021, China.
A bioassay-guided isolation of an ethanol extract of the fruit of Piper longum L. yielded piperlonguminine, piperine and pipernonaline, as the main lipid lowering constituents. They exhibit appreciable lipid lowering activity in vivo, which is comparable to that of the commercial lipid lowering drug, simvastatin.

Piper Longum research studies
Antiplatelet effects of acidamides isolated from the fruits of Piper longum L.
Phytomedicine. 2007 December. Institute of Ecological Phytochemistry, Hankyong National University, Ansung City, Kyonggi-Do 456-749, Republic of Korea.
The inhibitory effects of four acidamides, piperine, pipernonaline, piperoctadecalidine, and piperlongumine, isolated from the fruits of Piper longum L. on washed rabbit platelet aggregation were examined. All of the four tested acidamides showed dose-dependent inhibitory activities on washed rabbit platelet aggregation induced by collagen, arachidonic acid (AA), and platelet-activating factor (PAF), except for that induced by thrombin. Piperlongumine, in particular, showed stronger inhibitory effects than other acidamides to rabbit platelet aggregation induced by collagen, AA and PAF.

Piper species include
Piper longum herb
Piper methysticum herb
Piper nigrum

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